Palladium(0)-catalyzed asymmetric C(sp3)–H arylation using a chiral binol-derived phosphate and an achiral ligand† †Electronic supplementary information (ESI) available: Full optimization tables, procedural, spectral and X-ray crystallographic (CIF) data, and DFT calculations. CCDC 1486752 and 1486753. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04006c Click here for additional data file. Click here for additional data file.
نویسندگان
چکیده
The first efficient palladium(0)-catalyzed enantioselective C(sp)–H activation reaction using a catalytic chiral base and an achiral phosphine ligand is reported. Fine-tuning the binol-derived phosphoric acid pre-catalyst and the reaction conditions was found to be crucial to achieve high levels of enantioselectivity for a variety of indoline products containing both triand tetrasubstituted stereocenters.
منابع مشابه
Photoinduced single-crystal-to-single-crystal phase transition and photosalient effect of a gold(i) isocyanide complex with shortening of intermolecular aurophilic bonds† †Electronic supplementary information (ESI) available: X-ray crystallographic data, optical properties, DFT calculations, and other additional information. CCDC [987280 and 987281]. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02676d Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file.
متن کامل
Rhodium(i)-catalyzed stereoselective [4+2] cycloaddition of oxetanols with alkynes through C(sp3)–C(sp3) bond cleavage† †Electronic supplementary information (ESI) available. CCDC 1512439 and 1512440. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc05246k Click here for additional data file. Click here for additional data file.
متن کامل
A new approach to the asymmetric Mannich reaction catalyzed by chiral N,N′-dioxide–metal complexes† †Electronic supplementary information (ESI) available. CCDC 1448521 and 1480808.For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03902b Click here for additional data file. Click here for additional data file.
متن کامل
C–H arylation of triphenylene, naphthalene and related arenes using Pd/C† †Electronic supplementary information (ESI) available. CCDC 1013416 and 1013417. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc03051f Click here for additional data file. Click here for additional data file.
متن کامل
A comparative study of the coordination behavior of cyclo-P5 and cyclo-As5 ligand complexes towards the trinuclear Lewis acid complex (perfluoro-ortho-phenylene)mercury† †Electronic supplementary information (ESI) available: Details of the syntheses, X-ray diffraction analyses of all presented and related products and details of the DFT calculations. CCDC 1012615–1012624. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02353f Click here for additional data file. Click here for additional data file.
متن کامل